Would you feel comfortable flying knowing there was only one pilot in the cockpit? My quick take: Nope!
Federal Aviation Regulations require two pilots in the cockpit for obvious reasons. But there is a pilot shortage and airlines are under pressure to cut costs so now the industry is trying to amend that two-pilot requirement to just one pilot. This would be done with a bill currently before Congress called the Federal Aviation Administration reauthorization bill.
As you might imagine, pilots do not want this. There is ample evidence that two hands are better than one, especially in times of crisis. Pilots say that airlines should not prioritize cost-cutting over safety. Agree.